Darvocet/ Darvon/ Propoxyphene

Darvon, Darvocet and the generic Propoxyphene were used to treat moderate or severe pain. According to the FDA, "even when taken at recommended doses," these drugs cause "significant changes to the electrical activity of the heart." These risks reportedly outweigh any potential benefits from the drugs. In late 2010, the United States Food and Drug Administration reported receiving clinical data showing the use of the drug put users "at risk of potentially serious or even fatal heart rhythm abnormalities." In the wake of this information, Darvocet, Darvon and the generics were withdrawn from the market. The most dangerous side effects are those that affect the heart, including arrhythmia, heart attack and congestive heart failure, as well as nausea, loss of consciousness, tightness in the chest, and changes to a person's mental state. It's reported that in hospitalized patients, symptoms such as nausea, vomiting, and dizziness were seen as severe side effects of Darvon to occur most often.

The manufacturers of both Darvon and its acetaminophen and propoxyphene containing counterpart Darvocet, were instructed by the FDA to pull the propoxyphene products from the market in November 2010. Propoxyphene is an opioid medicine that has been marketed in approved drugs such as Darvon and Darvocet. Propoxyphene is used to relieve mild to moderate pain. Based on data submitted and available to the FDA, the Agency stated concersn about an increase risk of fatal overdose when using medicine continaing propoxyphene.